Posts by: Alice Melão

Alice Melão

January 4, 2019

Lynparza Approved in U.S. as First-line Maintenance Therapy for BRCA-positive Advanced Ovarian Cancer

News

Women with BRCA-mutated advanced ovarian cancer living in the United States can now receive Lynparza (olaparib), developed by AstraZeneca and Merck, as a maintenance treatment for their partial or complete response to ... Read more

November 12, 2018

Docetaxel Nanoparticle CPC634 in Phase 2 Trial for Platinum-resistant OC

News

Cristal Therapeutics has begun patient dosing in its Phase 2a trial evaluating CPC634 — the chemotherapy docetaxel, delivered in nanoparticles — in patients whose ovarian cancer has become resistant to ... Read more

October 26, 2018

Five Prime’s Phase 1 Trial Begins FPA150 Dosing Among Solid Tumor Patients

News

The Phase 1a/1b trial evaluating Five Prime Therapeutics‘ checkpoint inhibitor FPA150 in patients with advanced solid cancers has begun dosing patients ahead of schedule, the company announced. FPA150 is an antibody ... Read more

September 19, 2018

Upcoming Phase 2 Trial to Evaluate DPX-Survivac with Keytruda in Ovarian, Other Solid Tumors

News

IMV will soon launch a Phase 2 trial to examine the potential of its lead candidate DPX-Survivac in combination with Merck’s anti-PD-1 therapy, Keytruda (pembrolizumab), in five solid tumor types. The study is ... Read more

August 10, 2018

Collaboration Tests TRX518-Bavencio Combo in Phase 1/2 Trial of Solid Tumors

News

Leap Therapeutics is launching a Phase 1/2 clinical trial to test its immunotherapy TRX518 in combination with Bavencio (avelumab) and chemotherapy in advanced solid tumors, as part of a collaboration established with Merck KGaA and Pfizer — the ... Read more

July 20, 2018

Phase 1/2 Trial Begins on ONCOS-102, Imfinzi Combination in Advanced Ovarian, Colorectal Cancers

News

A new Phase 1/2 clinical trial has been launched testing a combination of investigational viral therapy ONCOS-102 and Imfinzi (durvalumab) in patients with advanced ovarian and colorectal cancers. The open-label ... Read more

July 6, 2018

Basilea Begins Phase 2a Expansion Trial Testing BAL101553 in Ovarian, Brain Cancers

News

Basilea Pharmaceutica has dosed its first patient in the expansion part of its Phase 1/2 trial (NCT02895360), which continues to explore the safety and effectiveness of BAL101553, an investigational tumor checkpoint ... Read more

June 29, 2018

AIVITA Advances Phase 2 Clinical Trial for Ovarian Cancer Vaccine

News

AIVITA Biomedical has begun to randomize patients for a Phase 2 clinical trial assessing its cell-based immunotherapy for the treatment of newly-diagnosed advanced ovarian cancer. Currently recruiting participants at Hoag Memorial Hospital ... Read more

June 18, 2018June 18, 2018

FDA Approves Avastin in Combination with Chemotherapy as Treatment for Advanced Ovarian Cancers

News

The U.S. Food and Drug Administration (FDA) has approved the use of Avastin (bevacizumab) in combination with standard chemotherapy, followed by Avastin alone, as a front-line treatment for advanced ... Read more

June 8, 2018

Phase 3 Trial Testing Pamiparib as Maintenance Therapy for Ovarian Cancer Recruiting Patients in China

News

BeiGene has started enrollment in its Phase 3 clinical trial evaluating the investigational PARP inhibitor pamiparib (BGB-290) as a maintenance therapy for ovarian cancer patients who are responding to platinum-based chemotherapy. ... Read more

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