BRCA1

August 2, 2019August 26, 2019

Gray Foundation Awards $3.75M to Study of BRCA Mutations in Ovarian and Other Cancers

News

The Gray Foundation awarded a $3.75 million grant to a researcher team to study how BRCA1 or BRCA2 mutations, along with other genetic anomalies, increase the risk of breast, ovarian, ... Read more

July 30, 2018

Loss of Certain Protein Identified in Ovarian Cancer Resistance to PARP Inhibitors

News

Researchers have identified a mechanism of resistance to PARP inhibitors — such as Lynparza (olaparib) and — in ovarian cancer, that involves the loss of a specific protein called 53BP1, according to ... Read more

May 14, 2018

Researchers Discover Mutations Behind Resistance to PARP Inhibitors Like Lynparza

News

Scientists have found mutations in the poly ADP-ribose polymerase (PARP) gene that cause resistance to PARP inhibitor therapies — such as Lynparza (olaparib) — in a mouse model and in one ... Read more

January 26, 2018

Genetic Testing for All Older Than 30 Would Prevent Many Ovarian and Breast Cancers, Study Says

News

Researchers argue in a new study that all women older than 30 should undergo screening for mutations in established risk genes for breast and ovarian cancer. Such a strategy, they ... Read more

August 25, 2017

Most Women with History of Ovarian or Breast Cancer Are Not Receiving Recommended Genetic Tests, Study Finds

News

Genetic screening to detect mutations that can predispose women to the development of breast or ovarian cancer has available since the mid-1990s. However, more than 80 percent of women at ... Read more

July 10, 2017July 10, 2017

BRCA1 and BRCA2 Mutations Increase Risk for Breast, Ovarian Cancers, Study Finds

News

Women who carry BRAC1 or BRAC2 genetic mutations have an increased risk of developing breast and ovarian cancers, according to a recent report published in JAMA. The study, “Risks of Breast, Ovarian, and Contralateral Breast ... Read more

December 5, 2016

Faster, Cheaper BRCA Gene-Testing Process Has Helped 1,000 UK Cancer Patients

News

One-thousand patients with ovarian cancer (OC) and breast cancer (BC) have now gained access to a faster BRCA gene-testing process due to an innovative approach developed by U.K. researchers that is showing ... Read more

December 2, 2016

Genetic Counseling Can Determine Risk for Ovarian, Other Cancers, and How to Manage Them

News

The University of Kentucky has released important information about how people can use genetic counseling to understand their risk of developing certain diseases, including ovarian cancer. With genetic counseling, patients ... Read more

November 21, 2016

UK Cancer Researcher Fights Disease Using Counterintuitive Approach

News

A researcher at Wellcome Trust/Cancer Research UK Gurdon Institute developed a counterintuitive approach to fighting cancer that led to the development of Lynparza (olaparib) as a prescribed medication for certain ... Read more

September 14, 2016

Expert: Ovarian Cancer Signs, Risk Factors Need More Emphasis

News

Gynecologic oncologist David Fishman, MD, is calling for a major shift in the prevention and treatment of ovarian cancer. According to Fishman, director of the cancer center and gynecologic oncology ... Read more