Loss of Certain Protein Identified in Ovarian Cancer Resistance to PARP Inhibitors

Loss of Certain Protein Identified in Ovarian Cancer Resistance to PARP Inhibitors
Researchers have identified a mechanism of resistance to PARP inhibitors — such as Lynparza (olaparib) and — in ovarian cancer, that involves the loss of a specific protein called 53BP1, according to a recent study. This finding may help physicians predict which cancer patients are more likely to develop a resistance to PARP inhibitors — based on the levels

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