Posts by: Alice Melão

News

The U.S. Food and Drug Administration (FDA) has approved DelMar Pharmaceuticals’ investigational new drug (IND) application for VAL-083 for the treatment of ovarian cancer. The IND approval allows the company ... Read more

September 20, 2017

CA4P Is Well Tolerated, May Benefit Platinum-resistant Ovarian Cancer Patients, Trial Shows

News

Data from the second interim analysis of the ongoing Phase 2/3 FOCUS study has shown that Mateon Therapeutics’ CA4P (combretastatin a4-phosphate), also known as fosbretabulin, may prolong the time to disease ... Read more

August 25, 2017

Most Women with History of Ovarian or Breast Cancer Are Not Receiving Recommended Genetic Tests, Study Finds

News

Genetic screening to detect mutations that can predispose women to the development of breast or ovarian cancer has available since the mid-1990s. However, more than 80 percent of women at ... Read more

August 18, 2017August 18, 2017

Diet May Be Reason Pitavastatin, a Statin, Failed to Arrest Ovarian Cancer in Clinical Trials, Study Says

News

Pitavastatin, part of a class of statins widely used to lower blood cholesterol levels, was found to successfully target ovarian cancer cells and reduce tumor growth in mice, according to a ... Read more

July 17, 2017July 17, 2017

Preventive Mastectomies Provide Little Survival Benefit for Ovarian Cancer Patients, Study Finds

News

Mastectomies and the removal of ovaries and fallopian tubes are considered preventive measures for women carrying BRCA genetic mutations linked to breast and ovarian cancer. But for women who have already had ... Read more

July 14, 2017July 14, 2017

Cancer Protein CA125 Blocks Investigational Therapy Farletuzumab’s Anti-Tumor Effectiveness, Study Finds

News

The protein CA125, which is commonly expressed on the surface of ovarian cancer cells and is secreted into the bloodstream, was found to block the activity of investigational drug farletuzumab. Farletuzumab ... Read more

July 12, 2017July 13, 2017

FDA Expands Use of DigniCap to Prevent Chemotherapy-induced Hair Loss

News

The DigniCap Cooling System, a scalp-cooling system designed by Dignitana to reduce hair loss due to chemotherapy, was cleared by the U.S. Food and Drug Administration (FDA) to be used ... Read more

July 10, 2017July 10, 2017

BRCA1 and BRCA2 Mutations Increase Risk for Breast, Ovarian Cancers, Study Finds

News

Women who carry BRAC1 or BRAC2 genetic mutations have an increased risk of developing breast and ovarian cancers, according to a recent report published in JAMA. The study, “Risks of Breast, Ovarian, and Contralateral Breast ... Read more

June 14, 2017June 14, 2017

Update on FOCUS Trial of CA4P in Ovarian Cancer Expected in Late Summer

News

Second preliminary results from the FOCUS Phase 2/3 trial assessing the safety and effectiveness of Mateon Therapeutics’ drug candidate CA4P in combination with standard-of-care therapies for platinum-resistant ovarian cancer are expected ... Read more

May 19, 2017May 19, 2017

Clear Cell Ovarian Cancer Patients Lacking ARID1A Protein Could Benefit from ENMD-2076 Treatment, Study Reports

News

Results from a Phase 2 clinical trial indicate that an investigational drug by CASI Pharmaceuticals, known as ENMD-2076, may be beneficial for patients with rare clear cell ovarian cancer (CCOC), particularly ... Read more