preclinical study

July 2, 2018July 2, 2018

Anti-cancer Protein, Once Reactivated, Seen to Target Ovarian Cancer Cells in Early Study

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Researchers have discovered how reactivating a protein called OPCML — a tumor suppressor molecule usually reduced or lost in cancer patients — works to suppress ovarian cancer cells. These findings ... Read more

May 9, 2018

Siamab’s ST1 Therapy Candidate Promising Against Chemoresistant Ovarian Cancer, Study Shows

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Siamab Therapeutics‘ investigational antibody-drug conjugate ST1 has promising anti-tumor effects against chemotherapy-resistant ovarian cancer in cell and animal models, a study shows. The study, “Treatment of ovarian cancer by targeting the tumor stem cell-associated ... Read more

March 19, 2018March 19, 2018

Leukemia Therapy Shows Potent Activity Against Rare Ovarian Cancer, Study Finds

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Ponatinib, an approved leukemia therapy sold under the brand name Iclusig, may be effective against tumors in a rare and aggressive form of ovarian cancer, research suggests. Led by researchers ... Read more

August 18, 2017August 18, 2017

Diet May Be Reason Pitavastatin, a Statin, Failed to Arrest Ovarian Cancer in Clinical Trials, Study Says

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Pitavastatin, part of a class of statins widely used to lower blood cholesterol levels, was found to successfully target ovarian cancer cells and reduce tumor growth in mice, according to a ... Read more