Posts by: Joana Carvalho, PhD

Joana Carvalho, PhD

Joana holds a BSc in Biology, a MSc in Evolutionary and Developmental Biology and a PhD in Biomedical Sciences from Universidade de Lisboa, Portugal. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — cells that made up the lining of blood vessels — found in the umbilical cord of newborns.

August 4, 2020August 4, 2020

Study: Tests Used to Predict Response to PARP Inhibitors Yield Inconsistent Result

News

Tests used in clinical trials of ovarian cancer to determine if tumors lack the ability to repair their DNA — a status termed “homologous recombination deficiency” (HRD), and likely ... Read more

July 23, 2020July 23, 2020

PARP Inhibitor Pamiparib Under Review in China to Treat Advanced Ovarian Cancer

News

China’s regulatory agency has agreed to consider a request that pamiparib, BeiGene‘s investigational PARP inhibitor, be approved to treat people with advanced ovarian cancers after at least two prior lines of ... Read more

July 7, 2020July 7, 2020

3D-PREDICT Trial Tests Kiyatec’s Predictor of Treatment Responses in Ovarian Cancer Patients

News

An ongoing observational registry study is evaluating Kiyatec‘s novel technology, in which a patient’s own tumor tissue is cultured in a lab dish and exposed to different therapies as ... Read more

June 23, 2020June 23, 2020

Protein Biomarkers to Gauge Cancer Response to Chemo Identified

News

Investigators using targeted proteomics — a technique to detect proteins of interest — on samples of ovarian cancer found a wide variety of biomarkers that might help predict which chemotherapies patients are ... Read more

June 18, 2020June 18, 2020

Mirvetuximab Soravtansine-Avastin Combo Linked to Promising Responses

News

When given alongside Avastin (bevacizumab), mirvetuximab soravtansine leads to promising treatment responses in women with recurrent ovarian cancer — particularly those whose tumors contain high levels of the protein ... Read more

June 4, 2020June 4, 2020

Genetic Testing for Breast, Ovarian Cancer Risk Safely Done at Home, Trial Shows

News

Genetic tests to assess the risk of breast and ovarian cancer can be performed remotely in the safety of the patients’ homes, according to data from an early Phase ... Read more

June 2, 2020June 2, 2020

Breastfeeding Lowers Risk of Ovarian Cancer for Decades, Study Finds

News

Women who breastfeed are at a significantly lower risk of developing ovarian cancer overall and some of its subtypes, including the deadliest — high-grade serous tumors, a large data study ... Read more

May 13, 2020May 13, 2020

Zejula-Avastin Combo Treating Advanced Cancer Patients in Phase 2 Trial

News

Zejula (niraparib) given in combination with Avastin (bevacizumab) shows promising safety and efficacy at delaying disease progression in women with advanced ovarian cancer who had responded to a first-line platinum-based ... Read more

May 6, 2020May 6, 2020

STRO-002 Continues to Show Promise in Advanced Ovarian Cancer, Early Trial Results Show

News

STRO-002, an investigational antibody-drug conjugate, continues to show promising safety and anti-tumor activity in women with advanced ovarian cancer, according to preliminary data from a Phase 1 clinical trial. ... Read more

April 15, 2020April 15, 2020

Antibody-drug Conjugate XMT-1536 Shows Promise for Ovarian Cancer in Phase 1 Trial

News

Treatment with XMT-1536 appears to be safe, with promising responses shown in heavily pretreated patients with ovarian cancer and non-small cell lung cancer (NSCLC) adenocarcinoma in a Phase 1 ... Read more

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