First Advanced Cancer Patients Dosed With VT1021 in Trial’s Expansion Phase

First Advanced Cancer Patients Dosed With VT1021 in Trial’s Expansion Phase
A Phase 1b/2 trial investigating Vigeo Therapeutics' VT1021 as a stand-alone treatment for advanced ovarian cancer and other tumor types has dosed the first patients in its dose expansion stage. Early results are expected later this year. Roughly 75 adults will be enrolled in this stage of the trial (NCT03364400). Besides ovarian cancer, the other groups will have patients with either pancreatic cancer, triple negative breast cancer, or glioblastoma — all of which express high levels of CD36, a cell surface protein receptor increasingly suggested as a target in cancer treatment. There is also a fifth group of patients with high CD36 expression but who are considered tissue agnostic, meaning that they have a different, although not specified, cancer type. Recruitment is ongoing across the United States. More information on contacts and locations is available here. "Advancing VT1021 in this study is a key milestone for Vigeo and we are excited to commence investigation of this promising agent in five patient group
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