Parsortix-based Blood Test Out-performs CA125 in Detecting Ovarian Cancer, Studies Show

Parsortix-based Blood Test Out-performs CA125 in Detecting Ovarian Cancer, Studies Show
Studies in the United States and Europe successfully demonstrate the potential of a Parsortix-based blood test to out-perform current tests in diagnosing ovarian cancer, Angle has recently announced. More specifically, the blood test demonstrates potential in discriminating between benign and malignant pelvic masses. Angle’s European study, ANG-001 (NCT02785731), is being led by Robert Zeillinger, PhD, at the Medical University of Vienna. The U.S. study, ANG-003 (NCT02781272), is being led by Richard Moore, MD, at the University of Rochester Medical Center, Wilmot Cancer Institute. According to the trials results, a test using the Parsortix system can successfully differentiate between benign and malignant masses with a high degree of sensitivity — up to 95 percent — while also achieving a low false-positive rate (higher specificity) than current options. The Parsortix system works by taking a blood sample (or liquid biopsy) from a patient. Then, a disposable microscope captures and harvests circulating tumor cells (CTCs) from the sample, based on the cells’ size and compressibility. A third step consists of selecting viable cells for analysis. Once captured and identified, the system reads RNA information within the cells, and informs clinicians about the patient's condition based on the results, helping to determine the most appropriate treatment. Advantages of this system include
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