First Successful Ovarian Transplant in Primates Shows Promise for Early Menopausal Women

First Successful Ovarian Transplant in Primates Shows Promise for Early Menopausal Women
Ovarian failure is a rare, but life-changing side effect of chemotherapy, triggering premature osteoporosis and at times preventing women from having biological children. But now, for reportedly the first time, researchers were able to successfully transplant an ovary from one primate to another, even managing to restore a monthly cycle, showing promise for patients who enter early menopause. The study, “Allogeneic transplantation of ovarian tissue with sole use of novel immunomodulator, preimplantation factor (PIF), restored ovarian function in baboons,” was presented at the American Society for Reproductive Medicine (ASRM) 2016 Scientific Congress & Expo Oct. 15-19 in Salt Lake City. In premature ovarian failure, women younger than 40 lose normal function of their ovaries. When ovaries fail, they stop producing normal amounts of estrogen and eggs are not released regularly. As a result, women often become infertile. Women with premature ovarian failure can, however, have irregular or occasional periods for years and might even become pregnant. "Firstly, an early menopause means that women cannot fulfill their longing for a child and, secondly, the associated drop in hormone levels can prematurely trigger osteoporosis or other menopausal complications," Michael Feichtinger, lead author of the study from MedUni Vienna's Department of Obstetrics and Gynecology, said in a news release. Although allo-transplantation (transplanting cells, tiss
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