Tiny 3-D Models May Offer Earlier Ovarian Cancer Diagnoses

Tiny 3-D Models May Offer Earlier Ovarian Cancer Diagnoses
CampanolaPA research team at the University of Wisconsin-Madison, led by professor of biomedical engineering and medical physics Paul Campagnola, is using innovative 3-D printing approaches to develop tools for imaging and detecting ovarian cancer. They aim to enhance scientific and medical understanding of how ovarian cancer cells develop and interact with nearby body tissue. Funded with a $2 million grant from the National Institutes of Health, the scientists are using technology they developed at UW-Madison to capture tissue images from surgical patients. The first target is collagen, a protein that holds bones, ligaments, and muscles together. ovepitheialA normal ovarian epithelial cell clings to a tiny model of an ovarian cancer tumor made with a 3-D printer. The tumor models will help scientists study ovarian cancer in mice, which do not naturally develop the disease. Image courtesy of Paul Campagnola "In most cancers, including ovarian, there are large changes in the collagen structure that goes along with the disease," Campagnola said in a UW-Madison press release. "It might happen firs
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