Pap Smear Samples May Aid Early Diagnosis of Common Ovarian Cancer

Pap Smear Samples May Aid Early Diagnosis of Common Ovarian Cancer
Genetic material collected in routine cervical cancer screenings could be used to screen for ovarian cancer several years before disease symptoms are evident, possible speeding diagnosis and treatment, a study suggests. The study, "Detection of TP53 Clonal Variants in Papanicolaou Test Samples Collected up to 6 Years Prior to High-Grade Serous Epithelial Ovarian Cancer Diagnosis," was published in JAMA Network Open. One of the ongoing challenges regarding ovarian cancer treatment and research is that, often, the cancer is not diagnosed until it is at a fairly advanced stage. More advanced cancers are generally associated with poorer outcomes; as such, there is a need for tests that can diagnose ovarian cancer at earlier stages, when it is more amenable to treatment. The Papanicolaou test — commonly referred to as a Pap smear — is a diagnostic tool that involves taking a sample of cells from the cervix to look at under a microscope. This test is routinely used to screen for cervical cancer, but
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