Women With Low LDL Have Lower Ovarian Cancer Risk, Genetic Analysis Shows

Women With Low LDL Have Lower Ovarian Cancer Risk, Genetic Analysis Shows
Women with naturally lower levels of LDL cholesterol have less risk of ovarian cancer, regardless of mutations in BRCA genes, a genetic analysis study revealed. The findings suggest a role for cholesterol-lowering statins to prevent the disease, though more research is needed to confirm that, the researchers said. The study, “Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer,” was published in the Journal of the American Medical Association. Observational studies have found that women who take statins have lower rates of ovarian cancer. And preclinical studies have shown that statins can also inhibit tumor growth and metastasis. However, these findings do not confirm a direct connection between statin therapy and ovarian cancer treatment. To better understand the connection, researchers at the University of Bristol in the U.K. designed a study to determine if wom
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