Changes in Gene Copy Number Sensitize Ovarian Cancer Cells to FDA-Approved Drugs, Study Finds

Changes in Gene Copy Number Sensitize Ovarian Cancer Cells to FDA-Approved Drugs, Study Finds
Gaining or losing a copy of a gene — a characteristic of cancer cells — disrupts specific signaling pathways and leads to cancer progression. Researchers studying these genetic alterations in ovarian cancer cells have found that a pathway involved in  autophagy —  a physiological process that deals with the destruction of cells — was the most affected by copy-number

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Inês Martins holds a BSc in Cell and Molecular Biology from Universidade Nova de Lisboa and is currently finishing her PhD in Biomedical Sciences at Universidade de Lisboa. Her work has been focused on blood vessels and their role in both hematopoiesis and cancer development.

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